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A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABA(A) receptors
Ion channels, like many other proteins, are composed of multiple structural domains. A stimulus that impinges on one domain, such as binding of a ligand to its recognition site, can influence the activity of another domain, such as a transmembrane channel gate, through interdomain interactions. Kine...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076519/ https://www.ncbi.nlm.nih.gov/pubmed/24981228 http://dx.doi.org/10.1085/jgp.201411183 |