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DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

Mast cells play a key role in the induction of anaphylaxis, a life-threatening IgE-dependent allergic reaction, by secreting chemical mediators that are stored in secretory granules. Degranulation of mast cells is triggered by aggregation of the high-affinity IgE receptor, FcεRI, and involves dynami...

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Detalles Bibliográficos
Autores principales:	Ogawa, Kana, Tanaka, Yoshihiko, Uruno, Takehito, Duan, Xuefeng, Harada, Yosuke, Sanematsu, Fumiyuki, Yamamura, Kazuhiko, Terasawa, Masao, Nishikimi, Akihiko, Côté, Jean-François, Fukui, Yoshinori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076576/ https://www.ncbi.nlm.nih.gov/pubmed/24913231 http://dx.doi.org/10.1084/jem.20131926

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