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Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapy

Loss of cell cycle controls is a hallmark of cancer and has a well-established role in aggressive B cell malignancies. However, the role of such lesions in indolent follicular lymphoma (FL) is unclear and individual lesions have been observed with low frequency. By analyzing genomic data from two la...

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Detalles Bibliográficos
Autores principales: Oricchio, Elisa, Ciriello, Giovanni, Jiang, Man, Boice, Michael H., Schatz, Jonathan H., Heguy, Adriana, Viale, Agnes, de Stanchina, Elisa, Teruya-Feldstein, Julie, Bouska, Alyssa, McKeithan, Tim, Sander, Chris, Tam, Wayne, Seshan, Venkatraman E., Chan, Wing-Chung, Chaganti, R.S.K., Wendel, Hans-Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076578/
https://www.ncbi.nlm.nih.gov/pubmed/24913233
http://dx.doi.org/10.1084/jem.20132120