Cargando…
Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapy
Loss of cell cycle controls is a hallmark of cancer and has a well-established role in aggressive B cell malignancies. However, the role of such lesions in indolent follicular lymphoma (FL) is unclear and individual lesions have been observed with low frequency. By analyzing genomic data from two la...
Autores principales: | Oricchio, Elisa, Ciriello, Giovanni, Jiang, Man, Boice, Michael H., Schatz, Jonathan H., Heguy, Adriana, Viale, Agnes, de Stanchina, Elisa, Teruya-Feldstein, Julie, Bouska, Alyssa, McKeithan, Tim, Sander, Chris, Tam, Wayne, Seshan, Venkatraman E., Chan, Wing-Chung, Chaganti, R.S.K., Wendel, Hans-Guido |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076578/ https://www.ncbi.nlm.nih.gov/pubmed/24913233 http://dx.doi.org/10.1084/jem.20132120 |
Ejemplares similares
-
Frequent 4EBP1 Amplification Induces Synthetic Dependence on FGFR Signaling in Cancer
por: Mohan, Prathibha, et al.
Publicado: (2022) -
Comparison of computational methods for the identification of topologically associating domains
por: Zufferey, Marie, et al.
Publicado: (2018) -
Multiple forms of tubulin in the cytoskeletal and flagellar microtubules of polytomella
por: McKeithan, TW, et al.
Publicado: (1981) -
NOXA genetic amplification or pharmacologic induction primes lymphoma cells to BCL2 inhibitor-induced cell death
por: Liu, Yuxuan, et al.
Publicado: (2018) -
Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
por: Schatz, Jonathan H., et al.
Publicado: (2011)