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Galectin-9 controls the therapeutic activity of 4-1BB–targeting antibodies

Biologics to TNF family receptors are prime candidates for therapy of immune disease. Whereas recent studies have highlighted a requirement for Fcγ receptors in enabling the activity of CD40, TRAILR, and GITR when engaged by antibodies, other TNFR molecules may be controlled by additional mechanisms...

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Detalles Bibliográficos
Autores principales: Madireddi, Shravan, Eun, So-Young, Lee, Seung-Woo, Nemčovičová, Ivana, Mehta, Amit Kumar, Zajonc, Dirk M., Nishi, Nozomu, Niki, Toshiro, Hirashima, Mitsuomi, Croft, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076583/
https://www.ncbi.nlm.nih.gov/pubmed/24958847
http://dx.doi.org/10.1084/jem.20132687