Cargando…
Cardiac fibroblasts mediate IL-17A–driven inflammatory dilated cardiomyopathy
Inflammatory dilated cardiomyopathy (DCMi) is a major cause of heart failure in individuals below the age of 40. We recently reported that IL-17A is required for the development of DCMi. We show a novel pathway connecting IL-17A, cardiac fibroblasts (CFs), GM-CSF, and heart-infiltrating myeloid cell...
Autores principales: | Wu, Lei, Ong, SuFey, Talor, Monica V., Barin, Jobert G., Baldeviano, G. Christian, Kass, David A., Bedja, Djahida, Zhang, Hao, Sheikh, Asfandyar, Margolick, Joseph B., Iwakura, Yoichiro, Rose, Noel R., Čiháková, Daniela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076595/ https://www.ncbi.nlm.nih.gov/pubmed/24935258 http://dx.doi.org/10.1084/jem.20132126 |
Ejemplares similares
-
Eosinophil-derived IL-4 drives progression of myocarditis to inflammatory dilated cardiomyopathy
por: Diny, Nicola L., et al.
Publicado: (2017) -
Complete Freund's adjuvant induces experimental autoimmune myocarditis by enhancing IL‐6 production during initiation of the immune response
por: Fontes, Jillian A., et al.
Publicado: (2017) -
Hypereosinophilia causes progressive cardiac pathologies in mice
por: Diny, Nicola Laura, et al.
Publicado: (2023) -
Pathogenic Roles of Cardiac Fibroblasts in Pediatric Dilated Cardiomyopathy
por: Tsuru, Hirofumi, et al.
Publicado: (2023) -
Combined effects of aging and inflammation on renin-angiotensin system mediate mitochondrial dysfunction and phenotypic changes in cardiomyopathies
por: Burks, Tyesha N., et al.
Publicado: (2015)