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Low-dose insulin-like growth factor binding proteins 1 and 2 and angiopoietin-like protein 3 coordinately stimulate ex vivo expansion of human umbilical cord blood hematopoietic stem cells as assayed in NOD/SCID gamma null mice

INTRODUCTION: Insulin-like growth factors (IGFs), IGF binding proteins (IGFBPs) and angiopoietin-like proteins (ANGPTLs) can enhance the ex vivo expansion of hematopoietic stem cells (HSCs) when used with a standard cytokine cocktail of stem cell factor (SCF), thrombopoietin (TPO) and FLT3 ligand (F...

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Detalles Bibliográficos
Autores principales:	Fan, Xiubo, Gay, Florence PH, Lim, Francesca WI, Ang, Justina ML, Chu, Pat PY, Bari, Sudipto, Hwang, William YK
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076633/ https://www.ncbi.nlm.nih.gov/pubmed/24886724 http://dx.doi.org/10.1186/scrt460

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