TAO1 kinase maintains chromosomal stability by facilitating proper congression of chromosomes

Chromosomal instability can arise from defects in chromosome–microtubule attachment. Using a variety of drug treatments, we show that TAO1 kinase is required for ensuring the normal congression of chromosomes. Depletion of TAO1 reduces the density of growing interphase and mitotic microtubules in hu...

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Detalles Bibliográficos
Autores principales: Shrestha, Roshan L., Tamura, Naoka, Fries, Anna, Levin, Nicolas, Clark, Joanna, Draviam, Viji M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077056/
https://www.ncbi.nlm.nih.gov/pubmed/24898139
http://dx.doi.org/10.1098/rsob.130108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077056/
https://www.ncbi.nlm.nih.gov/pubmed/24898139
http://dx.doi.org/10.1098/rsob.130108

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