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Assessment of a novel multi-array normalization method based on spike-in control probes suitable for microRNA datasets with global decreases in expression

BACKGROUND: High-quality expression data are required to investigate the biological effects of microRNAs (miRNAs). The goal of this study was, first, to assess the quality of miRNA expression data based on microarray technologies and, second, to consolidate it by applying a novel normalization metho...

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Detalles Bibliográficos
Autores principales:	Sewer, Alain, Gubian, Sylvain, Kogel, Ulrike, Veljkovic, Emilija, Han, Wanjiang, Hengstermann, Arnd, Peitsch, Manuel C, Hoeng, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077261/ https://www.ncbi.nlm.nih.gov/pubmed/24886675 http://dx.doi.org/10.1186/1756-0500-7-302

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