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A Huge PVDF Adsorption Difference Between Resveratrol and ε-Viniferin Allows to Quantitatively Purify Them and to Assess Their Anti-Tyrosinase Property

Repeated chromatographic analyses of polyphenolic vine stalks extracts allowed us to note a huge adsorption difference on polyvinylidene fluoride (PVDF), between trans-resveratrol 1 and (+)-trans-ε-viniferin 2. We could optimize the conditions (solvent, saturation of the process), for this polymer t...

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Autores principales: Morel-Salmi, Cécile, Julia, Audrey, Vigor, Claire, Vercauteren, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077311/
https://www.ncbi.nlm.nih.gov/pubmed/25067848
http://dx.doi.org/10.1007/s10337-014-2707-8
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author Morel-Salmi, Cécile
Julia, Audrey
Vigor, Claire
Vercauteren, Joseph
author_facet Morel-Salmi, Cécile
Julia, Audrey
Vigor, Claire
Vercauteren, Joseph
author_sort Morel-Salmi, Cécile
collection PubMed
description Repeated chromatographic analyses of polyphenolic vine stalks extracts allowed us to note a huge adsorption difference on polyvinylidene fluoride (PVDF), between trans-resveratrol 1 and (+)-trans-ε-viniferin 2. We could optimize the conditions (solvent, saturation of the process), for this polymer to adsorb very selectively 2, with regard to the monomer 1 that remains in solution. Since membrane filters made of PVDF are quite often used for HPLC samples filtration, this observation prompted us to inform phytochemists studying plant stilbenoid contents. Based on this background information, we developed a straightforward and inexpensive enrichment process for either 1 and/or 2, from crude Vitis vinifera stalks extracts, allowing to get them in a pure form. Having at hand large amounts of these two pure compounds, they were tested and compared to a set of other relevant molecules for some biological properties: trans-ε-viniferin 2 was shown to be the most powerful tyrosinase inhibitor, among all samples tested.
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spelling pubmed-40773112014-07-25 A Huge PVDF Adsorption Difference Between Resveratrol and ε-Viniferin Allows to Quantitatively Purify Them and to Assess Their Anti-Tyrosinase Property Morel-Salmi, Cécile Julia, Audrey Vigor, Claire Vercauteren, Joseph Chromatographia Short Communication Repeated chromatographic analyses of polyphenolic vine stalks extracts allowed us to note a huge adsorption difference on polyvinylidene fluoride (PVDF), between trans-resveratrol 1 and (+)-trans-ε-viniferin 2. We could optimize the conditions (solvent, saturation of the process), for this polymer to adsorb very selectively 2, with regard to the monomer 1 that remains in solution. Since membrane filters made of PVDF are quite often used for HPLC samples filtration, this observation prompted us to inform phytochemists studying plant stilbenoid contents. Based on this background information, we developed a straightforward and inexpensive enrichment process for either 1 and/or 2, from crude Vitis vinifera stalks extracts, allowing to get them in a pure form. Having at hand large amounts of these two pure compounds, they were tested and compared to a set of other relevant molecules for some biological properties: trans-ε-viniferin 2 was shown to be the most powerful tyrosinase inhibitor, among all samples tested. Springer Berlin Heidelberg 2014-06-15 2014 /pmc/articles/PMC4077311/ /pubmed/25067848 http://dx.doi.org/10.1007/s10337-014-2707-8 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Short Communication
Morel-Salmi, Cécile
Julia, Audrey
Vigor, Claire
Vercauteren, Joseph
A Huge PVDF Adsorption Difference Between Resveratrol and ε-Viniferin Allows to Quantitatively Purify Them and to Assess Their Anti-Tyrosinase Property
title A Huge PVDF Adsorption Difference Between Resveratrol and ε-Viniferin Allows to Quantitatively Purify Them and to Assess Their Anti-Tyrosinase Property
title_full A Huge PVDF Adsorption Difference Between Resveratrol and ε-Viniferin Allows to Quantitatively Purify Them and to Assess Their Anti-Tyrosinase Property
title_fullStr A Huge PVDF Adsorption Difference Between Resveratrol and ε-Viniferin Allows to Quantitatively Purify Them and to Assess Their Anti-Tyrosinase Property
title_full_unstemmed A Huge PVDF Adsorption Difference Between Resveratrol and ε-Viniferin Allows to Quantitatively Purify Them and to Assess Their Anti-Tyrosinase Property
title_short A Huge PVDF Adsorption Difference Between Resveratrol and ε-Viniferin Allows to Quantitatively Purify Them and to Assess Their Anti-Tyrosinase Property
title_sort huge pvdf adsorption difference between resveratrol and ε-viniferin allows to quantitatively purify them and to assess their anti-tyrosinase property
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077311/
https://www.ncbi.nlm.nih.gov/pubmed/25067848
http://dx.doi.org/10.1007/s10337-014-2707-8
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