Effects of the chemokine CXCL12 and combined internalization of its receptors CXCR4 and CXCR7 in human MCF-7 breast cancer cells

The chemokine CXCL12 (stromal cell-derived factor-1, SDF-1) and its receptor CXCR4 play a major role in tumor initiation, promotion, progression and metastasis, especially for breast cancer cells. Recently, CXCR7 has been identified as a second receptor for CXCL12; nevertheless, it also binds CXCL11...

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Detalles Bibliográficos
Autores principales: Hattermann, Kirsten, Holzenburg, Eric, Hans, Friederike, Lucius, Ralph, Held-Feindt, Janka, Mentlein, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077318/
https://www.ncbi.nlm.nih.gov/pubmed/24770893
http://dx.doi.org/10.1007/s00441-014-1823-y

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