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Sailfish enables alignment-free isoform quantification from RNA-seq reads using lightweight algorithms
We introduce Sailfish, a computational method for quantifying the abundance of previously annotated RNA isoforms from RNA-seq data. Because Sailfish entirely avoids mapping reads, a time-consuming step in all current methods, it provides quantification estimates much faster than do existing approach...
Autores principales: | Patro, Rob, Mount, Stephen M., Kingsford, Carl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077321/ https://www.ncbi.nlm.nih.gov/pubmed/24752080 http://dx.doi.org/10.1038/nbt.2862 |
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