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Asymmetric Ugi 3CR on isatin-derived ketimine: synthesis of chiral 3,3-disubstituted 3-aminooxindole derivatives

An efficient Ugi three-component reaction of a preformed chiral ketimine derived from isatin with various isonitrile and acid components has been developed. The reactions proceeded smoothly and in a stereocontrolled manner with regard to the new center of the Ugi products due to the stereoinduction...

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Detalles Bibliográficos
Autores principales:	Lesma, Giordano, Meneghetti, Fiorella, Sacchetti, Alessandro, Stucchi, Mattia, Silvani, Alessandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2014
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077467/ https://www.ncbi.nlm.nih.gov/pubmed/24991292 http://dx.doi.org/10.3762/bjoc.10.141

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