Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids

The synthesis of six cyclic depsipeptoids inspired by the natural depsipeptide sansalvamide A is described. An efficient and fast synthetic strategy was developed using a combination of consecutive isocyanide-based multicomponent reactions (Ugi and Passerini reactions). This methodology can be used...

Descripción completa

Detalles Bibliográficos
Autores principales: Barreto, Angélica de Fátima S, Vercillo, Otilie E, Wessjohann, Ludger A, Andrade, Carlos Kleber Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077530/
https://www.ncbi.nlm.nih.gov/pubmed/24991252
http://dx.doi.org/10.3762/bjoc.10.101
_version_ 1782323609235095552
author Barreto, Angélica de Fátima S
Vercillo, Otilie E
Wessjohann, Ludger A
Andrade, Carlos Kleber Z
author_facet Barreto, Angélica de Fátima S
Vercillo, Otilie E
Wessjohann, Ludger A
Andrade, Carlos Kleber Z
author_sort Barreto, Angélica de Fátima S
collection PubMed
description The synthesis of six cyclic depsipeptoids inspired by the natural depsipeptide sansalvamide A is described. An efficient and fast synthetic strategy was developed using a combination of consecutive isocyanide-based multicomponent reactions (Ugi and Passerini reactions). This methodology can be used to access a variety of cyclic oligodepsipeptoids.
format Online
Article
Text
id pubmed-4077530
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-40775302014-07-02 Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids Barreto, Angélica de Fátima S Vercillo, Otilie E Wessjohann, Ludger A Andrade, Carlos Kleber Z Beilstein J Org Chem Letter The synthesis of six cyclic depsipeptoids inspired by the natural depsipeptide sansalvamide A is described. An efficient and fast synthetic strategy was developed using a combination of consecutive isocyanide-based multicomponent reactions (Ugi and Passerini reactions). This methodology can be used to access a variety of cyclic oligodepsipeptoids. Beilstein-Institut 2014-05-05 /pmc/articles/PMC4077530/ /pubmed/24991252 http://dx.doi.org/10.3762/bjoc.10.101 Text en Copyright © 2014, Barreto et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Barreto, Angélica de Fátima S
Vercillo, Otilie E
Wessjohann, Ludger A
Andrade, Carlos Kleber Z
Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids
title Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids
title_full Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids
title_fullStr Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids
title_full_unstemmed Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids
title_short Consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids
title_sort consecutive isocyanide-based multicomponent reactions: synthesis of cyclic pentadepsipeptoids
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077530/
https://www.ncbi.nlm.nih.gov/pubmed/24991252
http://dx.doi.org/10.3762/bjoc.10.101
work_keys_str_mv AT barretoangelicadefatimas consecutiveisocyanidebasedmulticomponentreactionssynthesisofcyclicpentadepsipeptoids
AT vercillootiliee consecutiveisocyanidebasedmulticomponentreactionssynthesisofcyclicpentadepsipeptoids
AT wessjohannludgera consecutiveisocyanidebasedmulticomponentreactionssynthesisofcyclicpentadepsipeptoids
AT andradecarloskleberz consecutiveisocyanidebasedmulticomponentreactionssynthesisofcyclicpentadepsipeptoids

Ejemplares similares