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IP(3)-mediated STIM1 oligomerization requires intact mitochondrial Ca(2+) uptake

Mitochondria contribute to cell signaling by controlling store-operated Ca(2+) entry (SOCE). SOCE is activated by Ca(2+) release from the endoplasmic reticulum (ER), whereupon stromal interacting molecule 1 (STIM1) forms oligomers, redistributes to ER–plasma-membrane junctions and opens plasma membr...

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Detalles Bibliográficos
Autores principales: Deak, Andras T., Blass, Sandra, Khan, Muhammad J., Groschner, Lukas N., Waldeck-Weiermair, Markus, Hallström, Seth, Graier, Wolfgang F., Malli, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077590/
https://www.ncbi.nlm.nih.gov/pubmed/24806964
http://dx.doi.org/10.1242/jcs.149807