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A novel bidirectional positive-feedback loop between Wnt–β-catenin and EGFR–ERK plays a role in context-specific modulation of epithelial tissue regeneration
By operating as both a subunit of the cadherin complex and a key component of Wnt signalling, β-catenin acts as the lynchpin between cell–cell contact and transcriptional regulation of proliferation, coordinating epithelial tissue homeostasis and regeneration. The integration of multiple growth-regu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077591/ https://www.ncbi.nlm.nih.gov/pubmed/24816560 http://dx.doi.org/10.1242/jcs.150888 |