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Safety evaluation of poly(lactic-co-glycolic acid)/poly(lactic-acid) microspheres through intravitreal injection in rabbits

Poly(lactic-co-glycolic acid) (PLGA) and/or poly(lactic-acid) (PLA) microspheres are important drug delivery systems. This study investigated eye biocompatibility and safety of PLGA/PLA microspheres through intravitreal injection in rabbits. Normal New Zealand rabbits were randomly selected and rece...

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Detalles Bibliográficos
Autores principales: Rong, Xianfang, Yuan, Weien, Lu, Yi, Mo, Xiaofen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077605/
https://www.ncbi.nlm.nih.gov/pubmed/25028546
http://dx.doi.org/10.2147/IJN.S64100