A (90)Y-labelled anti-ROBO1 monoclonal antibody exhibits antitumour activity against hepatocellular carcinoma xenografts during ROBO1-targeted radioimmunotherapy

BACKGROUND: ROBO1 is a membrane protein that functions in axon guidance. ROBO1 contributes to tumour metastasis and angiogenesis and may have potential as a target protein of immunotherapy because ROBO1 is specifically expressed at high levels in hepatocellular carcinoma. In this study, we examined...

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Detalles Bibliográficos
Autores principales: Fujiwara, Kentaro, Koyama, Keitaro, Suga, Kosuke, Ikemura, Masako, Saito, Yasutaka, Hino, Akihiro, Iwanari, Hiroko, Kusano-Arai, Osamu, Mitsui, Kenichi, Kasahara, Hiroyuki, Fukayama, Masashi, Kodama, Tatsuhiko, Hamakubo, Takao, Momose, Toshimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077627/
https://www.ncbi.nlm.nih.gov/pubmed/25006547
http://dx.doi.org/10.1186/s13550-014-0029-3

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