Rapidly blinding posterior tubercular uveitis

BACKGROUND: A 21-year-old female patient had chorioretinitis in the left eye which relapsed while being on anti-tubercular treatment and oral corticosteroids leading to blindness and the loss of the left eye. FINDINGS: Mycobacterium tuberculosis causing chorioretinitis showed a poor response, and th...

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Detalles Bibliográficos
Autores principales: Agarwal, Manisha, Jha, Vivek, Biswas, Jyotirmay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077645/
https://www.ncbi.nlm.nih.gov/pubmed/25006352
http://dx.doi.org/10.1186/1869-5760-4-13
Descripción
Sumario:BACKGROUND: A 21-year-old female patient had chorioretinitis in the left eye which relapsed while being on anti-tubercular treatment and oral corticosteroids leading to blindness and the loss of the left eye. FINDINGS: Mycobacterium tuberculosis causing chorioretinitis showed a poor response, and the lung lesions showed a good response to the same anti-tubercular treatment. CONCLUSIONS: Mycobacterium tubercle bacilli in the eye may show a poor response to the anti-tubercular drugs due to poor ocular penetration of the drugs secondary to early ocular hypoxia.

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