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Rapidly blinding posterior tubercular uveitis
BACKGROUND: A 21-year-old female patient had chorioretinitis in the left eye which relapsed while being on anti-tubercular treatment and oral corticosteroids leading to blindness and the loss of the left eye. FINDINGS: Mycobacterium tuberculosis causing chorioretinitis showed a poor response, and th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077645/ https://www.ncbi.nlm.nih.gov/pubmed/25006352 http://dx.doi.org/10.1186/1869-5760-4-13 |
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author | Agarwal, Manisha Jha, Vivek Biswas, Jyotirmay |
author_facet | Agarwal, Manisha Jha, Vivek Biswas, Jyotirmay |
author_sort | Agarwal, Manisha |
collection | PubMed |
description | BACKGROUND: A 21-year-old female patient had chorioretinitis in the left eye which relapsed while being on anti-tubercular treatment and oral corticosteroids leading to blindness and the loss of the left eye. FINDINGS: Mycobacterium tuberculosis causing chorioretinitis showed a poor response, and the lung lesions showed a good response to the same anti-tubercular treatment. CONCLUSIONS: Mycobacterium tubercle bacilli in the eye may show a poor response to the anti-tubercular drugs due to poor ocular penetration of the drugs secondary to early ocular hypoxia. |
format | Online Article Text |
id | pubmed-4077645 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Springer |
record_format | MEDLINE/PubMed |
spelling | pubmed-40776452014-07-08 Rapidly blinding posterior tubercular uveitis Agarwal, Manisha Jha, Vivek Biswas, Jyotirmay J Ophthalmic Inflamm Infect Brief Report BACKGROUND: A 21-year-old female patient had chorioretinitis in the left eye which relapsed while being on anti-tubercular treatment and oral corticosteroids leading to blindness and the loss of the left eye. FINDINGS: Mycobacterium tuberculosis causing chorioretinitis showed a poor response, and the lung lesions showed a good response to the same anti-tubercular treatment. CONCLUSIONS: Mycobacterium tubercle bacilli in the eye may show a poor response to the anti-tubercular drugs due to poor ocular penetration of the drugs secondary to early ocular hypoxia. Springer 2014-06-09 /pmc/articles/PMC4077645/ /pubmed/25006352 http://dx.doi.org/10.1186/1869-5760-4-13 Text en Copyright © 2014 Agarwal et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Brief Report Agarwal, Manisha Jha, Vivek Biswas, Jyotirmay Rapidly blinding posterior tubercular uveitis |
title | Rapidly blinding posterior tubercular uveitis |
title_full | Rapidly blinding posterior tubercular uveitis |
title_fullStr | Rapidly blinding posterior tubercular uveitis |
title_full_unstemmed | Rapidly blinding posterior tubercular uveitis |
title_short | Rapidly blinding posterior tubercular uveitis |
title_sort | rapidly blinding posterior tubercular uveitis |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077645/ https://www.ncbi.nlm.nih.gov/pubmed/25006352 http://dx.doi.org/10.1186/1869-5760-4-13 |
work_keys_str_mv | AT agarwalmanisha rapidlyblindingposteriortubercularuveitis AT jhavivek rapidlyblindingposteriortubercularuveitis AT biswasjyotirmay rapidlyblindingposteriortubercularuveitis |