Cargando…

Rapidly blinding posterior tubercular uveitis

BACKGROUND: A 21-year-old female patient had chorioretinitis in the left eye which relapsed while being on anti-tubercular treatment and oral corticosteroids leading to blindness and the loss of the left eye. FINDINGS: Mycobacterium tuberculosis causing chorioretinitis showed a poor response, and th...

Descripción completa

Detalles Bibliográficos
Autores principales: Agarwal, Manisha, Jha, Vivek, Biswas, Jyotirmay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077645/
https://www.ncbi.nlm.nih.gov/pubmed/25006352
http://dx.doi.org/10.1186/1869-5760-4-13
_version_ 1782323627682693120
author Agarwal, Manisha
Jha, Vivek
Biswas, Jyotirmay
author_facet Agarwal, Manisha
Jha, Vivek
Biswas, Jyotirmay
author_sort Agarwal, Manisha
collection PubMed
description BACKGROUND: A 21-year-old female patient had chorioretinitis in the left eye which relapsed while being on anti-tubercular treatment and oral corticosteroids leading to blindness and the loss of the left eye. FINDINGS: Mycobacterium tuberculosis causing chorioretinitis showed a poor response, and the lung lesions showed a good response to the same anti-tubercular treatment. CONCLUSIONS: Mycobacterium tubercle bacilli in the eye may show a poor response to the anti-tubercular drugs due to poor ocular penetration of the drugs secondary to early ocular hypoxia.
format Online
Article
Text
id pubmed-4077645
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Springer
record_format MEDLINE/PubMed
spelling pubmed-40776452014-07-08 Rapidly blinding posterior tubercular uveitis Agarwal, Manisha Jha, Vivek Biswas, Jyotirmay J Ophthalmic Inflamm Infect Brief Report BACKGROUND: A 21-year-old female patient had chorioretinitis in the left eye which relapsed while being on anti-tubercular treatment and oral corticosteroids leading to blindness and the loss of the left eye. FINDINGS: Mycobacterium tuberculosis causing chorioretinitis showed a poor response, and the lung lesions showed a good response to the same anti-tubercular treatment. CONCLUSIONS: Mycobacterium tubercle bacilli in the eye may show a poor response to the anti-tubercular drugs due to poor ocular penetration of the drugs secondary to early ocular hypoxia. Springer 2014-06-09 /pmc/articles/PMC4077645/ /pubmed/25006352 http://dx.doi.org/10.1186/1869-5760-4-13 Text en Copyright © 2014 Agarwal et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Brief Report
Agarwal, Manisha
Jha, Vivek
Biswas, Jyotirmay
Rapidly blinding posterior tubercular uveitis
title Rapidly blinding posterior tubercular uveitis
title_full Rapidly blinding posterior tubercular uveitis
title_fullStr Rapidly blinding posterior tubercular uveitis
title_full_unstemmed Rapidly blinding posterior tubercular uveitis
title_short Rapidly blinding posterior tubercular uveitis
title_sort rapidly blinding posterior tubercular uveitis
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077645/
https://www.ncbi.nlm.nih.gov/pubmed/25006352
http://dx.doi.org/10.1186/1869-5760-4-13
work_keys_str_mv AT agarwalmanisha rapidlyblindingposteriortubercularuveitis
AT jhavivek rapidlyblindingposteriortubercularuveitis
AT biswasjyotirmay rapidlyblindingposteriortubercularuveitis