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Neuronal Injury External to the Retina Rapidly Activates Retinal Glia, Followed by Elevation of Markers for Cell Cycle Re-Entry and Death in Retinal Ganglion Cells
Retinal ganglion cells (RGCs) are neurons that relay visual signals from the retina to the brain. The RGC cell bodies reside in the retina and their fibers form the optic nerve. Full transection (axotomy) of the optic nerve is an extra-retinal injury model of RGC degeneration. Optic nerve transectio...
Autores principales: | Galan, Alba, Dergham, Pauline, Escoll, Pedro, de-la-Hera, Antonio, D'Onofrio, Philippe M., Magharious, Mark M., Koeberle, Paulo D., Frade, José María, Saragovi, H. Uri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077807/ https://www.ncbi.nlm.nih.gov/pubmed/24983470 http://dx.doi.org/10.1371/journal.pone.0101349 |
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