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Neuronal Injury External to the Retina Rapidly Activates Retinal Glia, Followed by Elevation of Markers for Cell Cycle Re-Entry and Death in Retinal Ganglion Cells

Retinal ganglion cells (RGCs) are neurons that relay visual signals from the retina to the brain. The RGC cell bodies reside in the retina and their fibers form the optic nerve. Full transection (axotomy) of the optic nerve is an extra-retinal injury model of RGC degeneration. Optic nerve transectio...

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Detalles Bibliográficos
Autores principales: Galan, Alba, Dergham, Pauline, Escoll, Pedro, de-la-Hera, Antonio, D'Onofrio, Philippe M., Magharious, Mark M., Koeberle, Paulo D., Frade, José María, Saragovi, H. Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077807/
https://www.ncbi.nlm.nih.gov/pubmed/24983470
http://dx.doi.org/10.1371/journal.pone.0101349

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