Significance of (18) F-FDG PET and immunohistochemical GLUT-1 expression for cardiac myxoma

Cardiac tumours are relatively rare and are difficult to diagnose merely with imaging techniques. We demonstrated an unusual case of left atrial myxoma, displaying the successful detection by positron emission tomography using 2-deoxy-2-[(18) F] fluoro-D-glucose ((18) F-FDG PET), correlated closely...

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Autores principales: Okazaki, Yukio, Yamada, Sohsuke, Kitada, Shohei, Matsunaga, Iwao, Nogami, Eijirou, Watanabe, Teruo, Sasaguri, Yasuyuki, Honma, Yutaka, Itou, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077832/
https://www.ncbi.nlm.nih.gov/pubmed/24934577
http://dx.doi.org/10.1186/1746-1596-9-117
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author Okazaki, Yukio
Yamada, Sohsuke
Kitada, Shohei
Matsunaga, Iwao
Nogami, Eijirou
Watanabe, Teruo
Sasaguri, Yasuyuki
Honma, Yutaka
Itou, Tsuyoshi
author_facet Okazaki, Yukio
Yamada, Sohsuke
Kitada, Shohei
Matsunaga, Iwao
Nogami, Eijirou
Watanabe, Teruo
Sasaguri, Yasuyuki
Honma, Yutaka
Itou, Tsuyoshi
author_sort Okazaki, Yukio
collection PubMed
description Cardiac tumours are relatively rare and are difficult to diagnose merely with imaging techniques. We demonstrated an unusual case of left atrial myxoma, displaying the successful detection by positron emission tomography using 2-deoxy-2-[(18) F] fluoro-D-glucose ((18) F-FDG PET), correlated closely to more intense and enhanced immunoreactivity with glucose transporter-1 (GLUT-1) in a substantial number of cardiac myxoma cells. Further prospective studies are needed to validate the significance of (18) F-FDG PET findings for cardiac myxoma and the association with immunohistochemical GLUT-1 expression in its tumour cells, after collecting and investigating a larger number of surgical cases examined with both of them. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2991481941253449
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spelling pubmed-40778322014-07-02 Significance of (18) F-FDG PET and immunohistochemical GLUT-1 expression for cardiac myxoma Okazaki, Yukio Yamada, Sohsuke Kitada, Shohei Matsunaga, Iwao Nogami, Eijirou Watanabe, Teruo Sasaguri, Yasuyuki Honma, Yutaka Itou, Tsuyoshi Diagn Pathol Letter to the Editor Cardiac tumours are relatively rare and are difficult to diagnose merely with imaging techniques. We demonstrated an unusual case of left atrial myxoma, displaying the successful detection by positron emission tomography using 2-deoxy-2-[(18) F] fluoro-D-glucose ((18) F-FDG PET), correlated closely to more intense and enhanced immunoreactivity with glucose transporter-1 (GLUT-1) in a substantial number of cardiac myxoma cells. Further prospective studies are needed to validate the significance of (18) F-FDG PET findings for cardiac myxoma and the association with immunohistochemical GLUT-1 expression in its tumour cells, after collecting and investigating a larger number of surgical cases examined with both of them. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2991481941253449 BioMed Central 2014-06-16 /pmc/articles/PMC4077832/ /pubmed/24934577 http://dx.doi.org/10.1186/1746-1596-9-117 Text en Copyright © 2014 Okazaki et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Okazaki, Yukio
Yamada, Sohsuke
Kitada, Shohei
Matsunaga, Iwao
Nogami, Eijirou
Watanabe, Teruo
Sasaguri, Yasuyuki
Honma, Yutaka
Itou, Tsuyoshi
Significance of (18) F-FDG PET and immunohistochemical GLUT-1 expression for cardiac myxoma
title Significance of (18) F-FDG PET and immunohistochemical GLUT-1 expression for cardiac myxoma
title_full Significance of (18) F-FDG PET and immunohistochemical GLUT-1 expression for cardiac myxoma
title_fullStr Significance of (18) F-FDG PET and immunohistochemical GLUT-1 expression for cardiac myxoma
title_full_unstemmed Significance of (18) F-FDG PET and immunohistochemical GLUT-1 expression for cardiac myxoma
title_short Significance of (18) F-FDG PET and immunohistochemical GLUT-1 expression for cardiac myxoma
title_sort significance of (18) f-fdg pet and immunohistochemical glut-1 expression for cardiac myxoma
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077832/
https://www.ncbi.nlm.nih.gov/pubmed/24934577
http://dx.doi.org/10.1186/1746-1596-9-117
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