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T cell immunosurveillance controls B lymphoma development

We recently showed a critical role for T cells in the immunosurveillance of nascent B cell lymphomas arising from mutations impacting plasma cell differentiation. Our data suggest that CD8(+) T cells continuously eliminate mutated B cells that fail to downregulate their co-stimulatory machinery and...

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Detalles Bibliográficos
Autor principal: Kallies, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077859/
https://www.ncbi.nlm.nih.gov/pubmed/25050223
http://dx.doi.org/10.4161/onci.28697