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T cell immunosurveillance controls B lymphoma development
We recently showed a critical role for T cells in the immunosurveillance of nascent B cell lymphomas arising from mutations impacting plasma cell differentiation. Our data suggest that CD8(+) T cells continuously eliminate mutated B cells that fail to downregulate their co-stimulatory machinery and...
Autor principal: | Kallies, Axel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077859/ https://www.ncbi.nlm.nih.gov/pubmed/25050223 http://dx.doi.org/10.4161/onci.28697 |
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