Transplantation-induced cancers: Emerging evidence that clonal CMV-specific NK cells are causal immunogenic factors

Solid cancers are a major adverse outcome of liver transplantation. Recent reassessments have revealed insights into causal factors, primarily centering on modulations of the natural killer (NK) cell compartment in liver transplant recipients. In the presence of cytomegalovirus, the clonal expansion...

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Autores principales: Achour, Abla, Baychelier, Florence, Marty, Michel, Debré, Patrice, Samuel, Didier, Vieillard, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077860/
https://www.ncbi.nlm.nih.gov/pubmed/25050225
http://dx.doi.org/10.4161/onci.28782
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author Achour, Abla
Baychelier, Florence
Marty, Michel
Debré, Patrice
Samuel, Didier
Vieillard, Vincent
author_facet Achour, Abla
Baychelier, Florence
Marty, Michel
Debré, Patrice
Samuel, Didier
Vieillard, Vincent
author_sort Achour, Abla
collection PubMed
description Solid cancers are a major adverse outcome of liver transplantation. Recent reassessments have revealed insights into causal factors, primarily centering on modulations of the natural killer (NK) cell compartment in liver transplant recipients. In the presence of cytomegalovirus, the clonal expansion of differentiated NK cells could restrict the diversity of the NK repertoire favoring the development of certain tumors.
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spelling pubmed-40778602014-07-21 Transplantation-induced cancers: Emerging evidence that clonal CMV-specific NK cells are causal immunogenic factors Achour, Abla Baychelier, Florence Marty, Michel Debré, Patrice Samuel, Didier Vieillard, Vincent Oncoimmunology Author's View Solid cancers are a major adverse outcome of liver transplantation. Recent reassessments have revealed insights into causal factors, primarily centering on modulations of the natural killer (NK) cell compartment in liver transplant recipients. In the presence of cytomegalovirus, the clonal expansion of differentiated NK cells could restrict the diversity of the NK repertoire favoring the development of certain tumors. Landes Bioscience 2014-04-29 /pmc/articles/PMC4077860/ /pubmed/25050225 http://dx.doi.org/10.4161/onci.28782 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Achour, Abla
Baychelier, Florence
Marty, Michel
Debré, Patrice
Samuel, Didier
Vieillard, Vincent
Transplantation-induced cancers: Emerging evidence that clonal CMV-specific NK cells are causal immunogenic factors
title Transplantation-induced cancers: Emerging evidence that clonal CMV-specific NK cells are causal immunogenic factors
title_full Transplantation-induced cancers: Emerging evidence that clonal CMV-specific NK cells are causal immunogenic factors
title_fullStr Transplantation-induced cancers: Emerging evidence that clonal CMV-specific NK cells are causal immunogenic factors
title_full_unstemmed Transplantation-induced cancers: Emerging evidence that clonal CMV-specific NK cells are causal immunogenic factors
title_short Transplantation-induced cancers: Emerging evidence that clonal CMV-specific NK cells are causal immunogenic factors
title_sort transplantation-induced cancers: emerging evidence that clonal cmv-specific nk cells are causal immunogenic factors
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077860/
https://www.ncbi.nlm.nih.gov/pubmed/25050225
http://dx.doi.org/10.4161/onci.28782
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