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Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy
The current practice of radiotherapy examines target coverage solely from digitally reconstructed beam’s eye view (BEV) in a way that is indirectly accessible and that is not in real time. We aimed to visualize treatment targets in real time from each BEV. The image data of phantom or patients from...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077863/ https://www.ncbi.nlm.nih.gov/pubmed/25028559 http://dx.doi.org/10.2147/OTT.S64161 |
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author | Chang, Wen-Chung Chen, Chin-Sheng Tai, Hung-Chi Liu, Chia-Yuan Chen, Yu-Jen |
author_facet | Chang, Wen-Chung Chen, Chin-Sheng Tai, Hung-Chi Liu, Chia-Yuan Chen, Yu-Jen |
author_sort | Chang, Wen-Chung |
collection | PubMed |
description | The current practice of radiotherapy examines target coverage solely from digitally reconstructed beam’s eye view (BEV) in a way that is indirectly accessible and that is not in real time. We aimed to visualize treatment targets in real time from each BEV. The image data of phantom or patients from ultrasound (US) and computed tomography (CT) scans were captured to perform image registration. We integrated US, CT, US/CT image registration, robotic manipulation of US, a radiation treatment planning system, and a linear accelerator to constitute an innovative target visualization system. The performance of this algorithm segmented the target organ in CT images, transformed and reconstructed US images to match each orientation, and generated image registration in real time mode with acceptable accuracy. This image transformation allowed physicians to visualize the CT image-reconstructed target via a US probe outside the BEV that was non-coplanar to the beam’s plane. It allowed the physicians to remotely control the US probe that was equipped on a robotic arm to dynamically trace and real time monitor the coverage of the target within the BEV during a simulated beam-on situation. This target visualization system may provide a direct remotely accessible and real time way to visualize, verify, and ensure tumor targeting during radiotherapy. |
format | Online Article Text |
id | pubmed-4077863 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-40778632014-07-15 Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy Chang, Wen-Chung Chen, Chin-Sheng Tai, Hung-Chi Liu, Chia-Yuan Chen, Yu-Jen Onco Targets Ther Original Research The current practice of radiotherapy examines target coverage solely from digitally reconstructed beam’s eye view (BEV) in a way that is indirectly accessible and that is not in real time. We aimed to visualize treatment targets in real time from each BEV. The image data of phantom or patients from ultrasound (US) and computed tomography (CT) scans were captured to perform image registration. We integrated US, CT, US/CT image registration, robotic manipulation of US, a radiation treatment planning system, and a linear accelerator to constitute an innovative target visualization system. The performance of this algorithm segmented the target organ in CT images, transformed and reconstructed US images to match each orientation, and generated image registration in real time mode with acceptable accuracy. This image transformation allowed physicians to visualize the CT image-reconstructed target via a US probe outside the BEV that was non-coplanar to the beam’s plane. It allowed the physicians to remotely control the US probe that was equipped on a robotic arm to dynamically trace and real time monitor the coverage of the target within the BEV during a simulated beam-on situation. This target visualization system may provide a direct remotely accessible and real time way to visualize, verify, and ensure tumor targeting during radiotherapy. Dove Medical Press 2014-06-23 /pmc/articles/PMC4077863/ /pubmed/25028559 http://dx.doi.org/10.2147/OTT.S64161 Text en © 2014 Chang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Chang, Wen-Chung Chen, Chin-Sheng Tai, Hung-Chi Liu, Chia-Yuan Chen, Yu-Jen Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy |
title | Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy |
title_full | Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy |
title_fullStr | Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy |
title_full_unstemmed | Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy |
title_short | Integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy |
title_sort | integration of multidisciplinary technologies for real time target visualization and verification for radiotherapy |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077863/ https://www.ncbi.nlm.nih.gov/pubmed/25028559 http://dx.doi.org/10.2147/OTT.S64161 |
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