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A critical role for natural killer cells in dendritic cell-based anticancer immunotherapy
Multipronged immunotherapies that activate both T cells and natural killer (NK) cells may result in more robust and durable anticancer responses. The successful outcome of dendritic cell (DC)-based vaccination therapy involves a hitherto unrecognized role for NK cells. Combinatorial regimens that en...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077866/ https://www.ncbi.nlm.nih.gov/pubmed/25050222 http://dx.doi.org/10.4161/onci.28582 |
| _version_ | 1782323669040627712 |
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| author | McLellan, Alexander D |
| author_facet | McLellan, Alexander D |
| author_sort | McLellan, Alexander D |
| collection | PubMed |
| description | Multipronged immunotherapies that activate both T cells and natural killer (NK) cells may result in more robust and durable anticancer responses. The successful outcome of dendritic cell (DC)-based vaccination therapy involves a hitherto unrecognized role for NK cells. Combinatorial regimens that enhance the contribution of NK cells to the anticancer immune response may therefore improve clinical outcomes. |
| format | Online Article Text |
| id | pubmed-4077866 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | Landes Bioscience |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-40778662014-07-21 A critical role for natural killer cells in dendritic cell-based anticancer immunotherapy McLellan, Alexander D Oncoimmunology Author's View Multipronged immunotherapies that activate both T cells and natural killer (NK) cells may result in more robust and durable anticancer responses. The successful outcome of dendritic cell (DC)-based vaccination therapy involves a hitherto unrecognized role for NK cells. Combinatorial regimens that enhance the contribution of NK cells to the anticancer immune response may therefore improve clinical outcomes. Landes Bioscience 2014-04-29 /pmc/articles/PMC4077866/ /pubmed/25050222 http://dx.doi.org/10.4161/onci.28582 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| spellingShingle | Author's View McLellan, Alexander D A critical role for natural killer cells in dendritic cell-based anticancer immunotherapy |
| title | A critical role for natural killer cells in dendritic cell-based anticancer immunotherapy |
| title_full | A critical role for natural killer cells in dendritic cell-based anticancer immunotherapy |
| title_fullStr | A critical role for natural killer cells in dendritic cell-based anticancer immunotherapy |
| title_full_unstemmed | A critical role for natural killer cells in dendritic cell-based anticancer immunotherapy |
| title_short | A critical role for natural killer cells in dendritic cell-based anticancer immunotherapy |
| title_sort | critical role for natural killer cells in dendritic cell-based anticancer immunotherapy |
| topic | Author's View |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077866/ https://www.ncbi.nlm.nih.gov/pubmed/25050222 http://dx.doi.org/10.4161/onci.28582 |
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