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Bikinin-like inhibitors targeting GSK3/Shaggy-like kinases: characterisation of novel compounds and elucidation of their catabolism in planta

BACKGROUND: Plant GSK-3/Shaggy-like kinases are key players in brassinosteroid (BR) signalling which impact on plant development and participate in response to wounding, pathogens and salt stress. Bikinin was previously identified in a chemical genetics screen as an inhibitor targeting these kinases...

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Detalles Bibliográficos
Autores principales: Rozhon, Wilfried, Wang, Wuyan, Berthiller, Franz, Mayerhofer, Juliane, Chen, Tingting, Petutschnig, Elena, Sieberer, Tobias, Poppenberger, Brigitte, Jonak, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078015/
https://www.ncbi.nlm.nih.gov/pubmed/24947596
http://dx.doi.org/10.1186/1471-2229-14-172