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Dopamine D(4) receptors inhibit proliferation and migration of vascular smooth muscle cells induced by insulin via down-regulation of insulin receptor expression
Vascular smooth muscle cells (VSMCs) proliferation and migration, which are central in the development of vascular diseases, are regulated by numerous hormones and humoral factors. Activation of the insulin receptor stimulates VSMCs proliferation while dopamine receptors, via D(1) and D(3) receptors...
Autores principales: | Yu, Changqing, Wang, Zhen, Han, Yu, Liu, Yukai, Wang, Wei Eric, Chen, Caiyu, Wang, Hongyong, Jose, Pedro A, Zeng, Chunyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078019/ https://www.ncbi.nlm.nih.gov/pubmed/24888351 http://dx.doi.org/10.1186/1475-2840-13-97 |
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