An approach for conjugation of (177)Lu- DOTA-SCN- Rituximab (BioSim) & its evaluation for radioimmunotherapy of relapsed & refractory B-cell non Hodgkins lymphoma patients

BACKGROUND & OBJECTIVES: The prerequisite of radioimmunotherapy is stable binding of a radionuclide to monoclonal antibodies, which are specific to the tumour-associated antigen. Most B-cell lymphomas express CD20 antigen on the surface of the tumour cells, making it a suitable target for therap...

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Detalles Bibliográficos
Autores principales: Thakral, Parul, Singla, Suhas, Yadav, Madhav Prasad, Vasisht, Atul, Sharma, Atul, Gupta, Santosh Kumar, Bal, C.S., Snehlata, Malhotra, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078492/
https://www.ncbi.nlm.nih.gov/pubmed/24927340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078492/
https://www.ncbi.nlm.nih.gov/pubmed/24927340

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