CYP4F2 1347 G>A & GGCX 12970 C>G polymorphisms: frequency in north Indians & their effect on dosing of acenocoumarol oral anticoagulant

BACKGROUND & OBJECTIVES: CYP4F2 and γ-glutamyl carboxylase (GGCX) have small but significant roles in the maintenance dose of coumarinic oral anticoagulants (COAs). CYP4F2 1347 G>A and GGCX 12970 C>G polymorphisms have been used in the pharmacogenetic dosing algorithms of warfarin for Cauc...

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Detalles Bibliográficos
Autores principales: Rathore, Saurabh Singh, Agarwal, Surendra Kumar, Pande, Shantanu, Singh, Sushil Kumar, Mittal, Tulika, Mittal, Balraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
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Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078496/
https://www.ncbi.nlm.nih.gov/pubmed/24927344

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