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Part Two: Evaluation of N-methylbupropion as a Potential Bupropion Prodrug
N-methylbupropion was selected as a potential prodrug from our in vitro screening of analogues of bupropion described in the preceding paper. This study describes in vivo pharmacokinetics of N-methylbupropion in the guinea-pig animal model, which is reported to best predict human metabolism of bupro...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078515/ https://www.ncbi.nlm.nih.gov/pubmed/24878537 http://dx.doi.org/10.3390/ph7060676 |