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Unusual occurrence of supratentorial medulloepithelioma in a young female

Medulloepithelioma is an extremely rare PNET in late adolescence and adults with only two cases noted in literature. These are WHO grade IV tumors with dismal prognosis. Only few cases survived beyond 5 months. We report a rare case of supratentorial medulloepithelioma in a 17 year old girl. She had...

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Autores principales: Ramesh, Andi Sadayandi, Anita, Mahadevan, Jitender, Saini, Somanna, Sampath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078611/
https://www.ncbi.nlm.nih.gov/pubmed/25002766
http://dx.doi.org/10.4103/0976-3147.133582
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author Ramesh, Andi Sadayandi
Anita, Mahadevan
Jitender, Saini
Somanna, Sampath
author_facet Ramesh, Andi Sadayandi
Anita, Mahadevan
Jitender, Saini
Somanna, Sampath
author_sort Ramesh, Andi Sadayandi
collection PubMed
description Medulloepithelioma is an extremely rare PNET in late adolescence and adults with only two cases noted in literature. These are WHO grade IV tumors with dismal prognosis. Only few cases survived beyond 5 months. We report a rare case of supratentorial medulloepithelioma in a 17 year old girl. She had presented with right sided weakness, headache and vomiting. Imaging showed an enhancing mass lesion in left parietal region which undergone gross total resection. After surgery, her headache, vomiting and right sided weakness improved. On histopathology, the tumor had characteristic trabecular, ribbon and palisaded arrangement with brisk mitotic activity, necrosis and calcification. Immuno-histochemistry revealed positivity for Synaptophysin, Vimentin and EMA while GFAP was negative. MIB-1 labeling was very high. Patient received postoperative radiotherapy. On follow up after 14 months, she was clinically asymptomatic with no recurrence on imaging.
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spelling pubmed-40786112014-07-07 Unusual occurrence of supratentorial medulloepithelioma in a young female Ramesh, Andi Sadayandi Anita, Mahadevan Jitender, Saini Somanna, Sampath J Neurosci Rural Pract Case Report Medulloepithelioma is an extremely rare PNET in late adolescence and adults with only two cases noted in literature. These are WHO grade IV tumors with dismal prognosis. Only few cases survived beyond 5 months. We report a rare case of supratentorial medulloepithelioma in a 17 year old girl. She had presented with right sided weakness, headache and vomiting. Imaging showed an enhancing mass lesion in left parietal region which undergone gross total resection. After surgery, her headache, vomiting and right sided weakness improved. On histopathology, the tumor had characteristic trabecular, ribbon and palisaded arrangement with brisk mitotic activity, necrosis and calcification. Immuno-histochemistry revealed positivity for Synaptophysin, Vimentin and EMA while GFAP was negative. MIB-1 labeling was very high. Patient received postoperative radiotherapy. On follow up after 14 months, she was clinically asymptomatic with no recurrence on imaging. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4078611/ /pubmed/25002766 http://dx.doi.org/10.4103/0976-3147.133582 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ramesh, Andi Sadayandi
Anita, Mahadevan
Jitender, Saini
Somanna, Sampath
Unusual occurrence of supratentorial medulloepithelioma in a young female
title Unusual occurrence of supratentorial medulloepithelioma in a young female
title_full Unusual occurrence of supratentorial medulloepithelioma in a young female
title_fullStr Unusual occurrence of supratentorial medulloepithelioma in a young female
title_full_unstemmed Unusual occurrence of supratentorial medulloepithelioma in a young female
title_short Unusual occurrence of supratentorial medulloepithelioma in a young female
title_sort unusual occurrence of supratentorial medulloepithelioma in a young female
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078611/
https://www.ncbi.nlm.nih.gov/pubmed/25002766
http://dx.doi.org/10.4103/0976-3147.133582
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