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A Fungal Glycosphingolipid Directly Activates Natural Killer T Cells and Rapidly Induces Airways Disease

Aspergillus fumigatusis a saprophytic fungus that is ubiquitous in the environment and commonly associated with allergic sensitization and severe asthma in humans. Although A. fumigatus is recognized by multiple microbial pattern recognition receptors, we identified and synthesized an A. fumigatus g...

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Detalles Bibliográficos
Autores principales: Albacker, Lee A., Chaudhary, Vinod, Chang, Ya-Jen, Kim, Hye Young, Chuang, Ya-Ting, Pichavant, Muriel, DeKruyff, Rosemarie H., Savage, Paul B., Umetsu, Dale T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079117/
https://www.ncbi.nlm.nih.gov/pubmed/23995283
http://dx.doi.org/10.1038/nm.3321