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A Fungal Glycosphingolipid Directly Activates Natural Killer T Cells and Rapidly Induces Airways Disease
Aspergillus fumigatusis a saprophytic fungus that is ubiquitous in the environment and commonly associated with allergic sensitization and severe asthma in humans. Although A. fumigatus is recognized by multiple microbial pattern recognition receptors, we identified and synthesized an A. fumigatus g...
Autores principales: | Albacker, Lee A., Chaudhary, Vinod, Chang, Ya-Jen, Kim, Hye Young, Chuang, Ya-Ting, Pichavant, Muriel, DeKruyff, Rosemarie H., Savage, Paul B., Umetsu, Dale T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079117/ https://www.ncbi.nlm.nih.gov/pubmed/23995283 http://dx.doi.org/10.1038/nm.3321 |
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