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Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation
BACKGROUND: Hepatocellular carcinoma (HCC), the primary liver cancer, is one of the most malignant human tumors with extremely poor prognosis. The aim of this study was to investigate the anti-cancer effect of berberine in a human hepatocellular carcinoma cell line (HepG2), and to study the underlyi...
Autores principales: | Yu, Rong, Zhang, Zhi-qing, Wang, Bin, Jiang, Hong-xin, Cheng, Lei, Shen, Li-ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079188/ https://www.ncbi.nlm.nih.gov/pubmed/24991192 http://dx.doi.org/10.1186/1475-2867-14-49 |
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