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Targeting Class A and C Serine β-Lactamases with a Broad-Spectrum Boronic Acid Derivative
[Image: see text] Production of β-lactamases (BLs) is the most widespread resistance mechanism adopted by bacteria to fight β-lactam antibiotics. The substrate spectrum of BLs has become increasingly broad, posing a serious health problem. Thus, there is an urgent need for novel BL inhibitors. Boron...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079326/ https://www.ncbi.nlm.nih.gov/pubmed/24882105 http://dx.doi.org/10.1021/jm5006572 |