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Effects of metaphyseal bone tumor removal with preservation of the epiphysis and knee arthroplasty

In this study, the effects of surgical removal of malignant metaphyseal bone tumors with epiphysis preservation and knee arthroplasty were analyzed. A total of 15 patients with malignant metaphyseal bone tumors were investigated. Six of these patients underwent epiphyseal preservation surgery with p...

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Autores principales: ZHANG, PENG, FENG, FEIFEI, CAI, QIQING, YAO, WEITAO, GAO, SONGTAO, WANG, JIAQIANG, WANG, XIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079396/
https://www.ncbi.nlm.nih.gov/pubmed/25009621
http://dx.doi.org/10.3892/etm.2014.1744
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author ZHANG, PENG
FENG, FEIFEI
CAI, QIQING
YAO, WEITAO
GAO, SONGTAO
WANG, JIAQIANG
WANG, XIN
author_facet ZHANG, PENG
FENG, FEIFEI
CAI, QIQING
YAO, WEITAO
GAO, SONGTAO
WANG, JIAQIANG
WANG, XIN
author_sort ZHANG, PENG
collection PubMed
description In this study, the effects of surgical removal of malignant metaphyseal bone tumors with epiphysis preservation and knee arthroplasty were analyzed. A total of 15 patients with malignant metaphyseal bone tumors were investigated. Six of these patients underwent epiphyseal preservation surgery with preoperative physeal distraction, termed the physeal distraction (PD) group. Nine patients underwent resection of the knee joint, combined with metal prosthesis transfer, termed the knee arthroplasty (KA) group. Tumor control, limb length discrepancy, range of movement (ROM) of the knee and functional outcome of lower limb [Musculoskeletal Tumor Society (MSTS) score and the Toronto extremity salvage score (TESS)] were assessed for these two groups. All 15 patients were followed-up after the surgery. One patient in the PD group was found to have lung tumor metastasis; however, no local tumor recurrence was found. In the KA group, local tumor recurrence was found in one patient, and lung metastases were observed in two cases postoperatively. The limb length discrepancy in patients of the PD group was 2.58±0.27 cm, which was significantly less compared with that in patients in the KA group (4.01±0.13 cm; P<0.05). In addition, the lower limb knee ROM in patients in the PD group was 127.70±14.63°, which was increased compared to that in patients in the KA group (105.70±15.48°; P<0.05). The mean MSTS score was 86.67% with a mean TESS of 82.33% in patients from the PD group, which showed no significant difference compared with the respective scores for patients in the KA group (P>0.05). Therefore, epiphyseal sparing limb-saving surgeries should be considered for the treatment of malignant metaphyseal bone tumors in children, when certain indications are satisfied.
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spelling pubmed-40793962014-07-09 Effects of metaphyseal bone tumor removal with preservation of the epiphysis and knee arthroplasty ZHANG, PENG FENG, FEIFEI CAI, QIQING YAO, WEITAO GAO, SONGTAO WANG, JIAQIANG WANG, XIN Exp Ther Med Articles In this study, the effects of surgical removal of malignant metaphyseal bone tumors with epiphysis preservation and knee arthroplasty were analyzed. A total of 15 patients with malignant metaphyseal bone tumors were investigated. Six of these patients underwent epiphyseal preservation surgery with preoperative physeal distraction, termed the physeal distraction (PD) group. Nine patients underwent resection of the knee joint, combined with metal prosthesis transfer, termed the knee arthroplasty (KA) group. Tumor control, limb length discrepancy, range of movement (ROM) of the knee and functional outcome of lower limb [Musculoskeletal Tumor Society (MSTS) score and the Toronto extremity salvage score (TESS)] were assessed for these two groups. All 15 patients were followed-up after the surgery. One patient in the PD group was found to have lung tumor metastasis; however, no local tumor recurrence was found. In the KA group, local tumor recurrence was found in one patient, and lung metastases were observed in two cases postoperatively. The limb length discrepancy in patients of the PD group was 2.58±0.27 cm, which was significantly less compared with that in patients in the KA group (4.01±0.13 cm; P<0.05). In addition, the lower limb knee ROM in patients in the PD group was 127.70±14.63°, which was increased compared to that in patients in the KA group (105.70±15.48°; P<0.05). The mean MSTS score was 86.67% with a mean TESS of 82.33% in patients from the PD group, which showed no significant difference compared with the respective scores for patients in the KA group (P>0.05). Therefore, epiphyseal sparing limb-saving surgeries should be considered for the treatment of malignant metaphyseal bone tumors in children, when certain indications are satisfied. D.A. Spandidos 2014-08 2014-05-28 /pmc/articles/PMC4079396/ /pubmed/25009621 http://dx.doi.org/10.3892/etm.2014.1744 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
ZHANG, PENG
FENG, FEIFEI
CAI, QIQING
YAO, WEITAO
GAO, SONGTAO
WANG, JIAQIANG
WANG, XIN
Effects of metaphyseal bone tumor removal with preservation of the epiphysis and knee arthroplasty
title Effects of metaphyseal bone tumor removal with preservation of the epiphysis and knee arthroplasty
title_full Effects of metaphyseal bone tumor removal with preservation of the epiphysis and knee arthroplasty
title_fullStr Effects of metaphyseal bone tumor removal with preservation of the epiphysis and knee arthroplasty
title_full_unstemmed Effects of metaphyseal bone tumor removal with preservation of the epiphysis and knee arthroplasty
title_short Effects of metaphyseal bone tumor removal with preservation of the epiphysis and knee arthroplasty
title_sort effects of metaphyseal bone tumor removal with preservation of the epiphysis and knee arthroplasty
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079396/
https://www.ncbi.nlm.nih.gov/pubmed/25009621
http://dx.doi.org/10.3892/etm.2014.1744
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