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Effect of osteopontin on TIMP-1 and TIMP-2 mRNA in chondrocytes of human knee osteoarthritis in vitro

Tissue inhibitors of metalloproteinases (TIMPs) regulate the activity of matrix metalloproteinases (MMPs) and enzymes from the a disintegrin and metalloproteinase domain with thrombospondin motifs family in osteoarthritis (OA). Elevated osteopontin (OPN) levels in plasma, synovial fluid and articula...

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Detalles Bibliográficos
Autores principales:	ZHANG, FANG-JIE, YU, WEN-BO, LUO, WEI, GAO, SHU-GUANG, LI, YU-SHENG, LEI, GUANG-HUA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079415/ https://www.ncbi.nlm.nih.gov/pubmed/25009588 http://dx.doi.org/10.3892/etm.2014.1750

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