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Construction and verification of the targeted uPA-shRNA lentiviral vector and evaluation of the transfection and silencing rate

Urokinase-type plasminogen activator (uPA) receptors, which are released by the synovial tissue, are responsible for the activation of cartilage-breakdown proteases and play critical roles in cartilage degradation during the progression of osteoarthritis (OA). RNA interference (RNAi) technology has...

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Detalles Bibliográficos
Autores principales:	WANG, WEI-SHAN, GUO, FENG-JING, LI, CHANG-JUN, ZHANG, ZHEN-DONG, SHI, CHEN-HUI
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079424/ https://www.ncbi.nlm.nih.gov/pubmed/25009597 http://dx.doi.org/10.3892/etm.2014.1741

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