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Activation of Nrf2 Protects against Triptolide-Induced Hepatotoxicity
Triptolide, the major active component of Tripterygium wilfordii Hook f. (TWHF), has a wide range of pharmacological activities. However, the toxicities of triptolide, particularly the hepatotoxicity, limit its clinical application. The hepatotoxicity of triptolide has not been well characterized ye...
Autores principales: | Li, Jia, Shen, Feihai, Guan, Cuiwen, Wang, Wenwen, Sun, Xiaozhe, Fu, Xinlu, Huang, Min, Jin, Jing, Huang, Zhiying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079517/ https://www.ncbi.nlm.nih.gov/pubmed/24988078 http://dx.doi.org/10.1371/journal.pone.0100685 |
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