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Clinical hypothermia temperatures increase complement activation and cell destruction via the classical pathway
BACKGROUND: Therapeutic hypothermia is a treatment modality that is increasingly used to improve clinical neurological outcomes for ischemia-reperfusion injury-mediated diseases. Antibody-initiated classical complement pathway activation has been shown to contribute to ischemia-reperfusion injury in...
Autores principales: | Shah, Tushar A, Mauriello, Clifford T, Hair, Pamela S, Sandhu, Amandeep, Stolz, Michael P, Bass, William Thomas, Krishna, Neel K, Cunnion, Kenji M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079622/ https://www.ncbi.nlm.nih.gov/pubmed/24962100 http://dx.doi.org/10.1186/1479-5876-12-181 |
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