Effect of vasopressin antagonism on renal handling of sodium and water and central and brachial blood pressure during inhibition of the nitric oxide system in healthy subjects

BACKGROUND: Tolvaptan is a selective vasopressin receptor antagonist (V2R) that increases free water excretion. We wanted to test the hypotheses that tolvaptan changes both renal handling of water and sodium and systemic hemodynamics during basal conditions and during nitric oxide (NO)-inhibition wi...

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Detalles Bibliográficos
Autores principales: Al Therwani, Safa, Mose, Frank Holden, Jensen, Janni Majgaard, Bech, Jesper Nørgaard, Pedersen, Erling Bjerregaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079642/
https://www.ncbi.nlm.nih.gov/pubmed/24965902
http://dx.doi.org/10.1186/1471-2369-15-100

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