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Optimization of Plasma Sample Pretreatment for Quantitative Analysis Using iTRAQ Labeling and LC-MALDI-TOF/TOF

Shotgun proteomic methods involving iTRAQ (isobaric tags for relative and absolute quantitation) peptide labeling facilitate quantitative analyses of proteomes and searches for useful biomarkers. However, the plasma proteome's complexity and the highly dynamic plasma protein concentration range...

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Detalles Bibliográficos
Autores principales: Luczak, Magdalena, Marczak, Lukasz, Stobiecki, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079693/
https://www.ncbi.nlm.nih.gov/pubmed/24988083
http://dx.doi.org/10.1371/journal.pone.0101694