Peripheral administration of morphine attenuates postincisional pain by regulating macrophage polarization through COX-2-dependent pathway

BACKGROUND: Macrophage infiltration to inflammatory sites promotes wound repair and may be involved in pain hypersensitivity after surgical incision. We recently reported that the development of hyperalgesia during chronic inflammation is regulated by macrophage polarity, often referred to as proinf...

Descripción completa

Detalles Bibliográficos
Autores principales: Godai, Kohei, Hasegawa-Moriyama, Maiko, Kurimoto, Tae, Saito, Takayuki, Yamada, Tomotsugu, Sato, Takahiro, Kojima, Masayasu, Kanmura, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079829/
https://www.ncbi.nlm.nih.gov/pubmed/24928142
http://dx.doi.org/10.1186/1744-8069-10-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079829/
https://www.ncbi.nlm.nih.gov/pubmed/24928142
http://dx.doi.org/10.1186/1744-8069-10-36

Ejemplares similares