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Peripheral administration of morphine attenuates postincisional pain by regulating macrophage polarization through COX-2-dependent pathway
BACKGROUND: Macrophage infiltration to inflammatory sites promotes wound repair and may be involved in pain hypersensitivity after surgical incision. We recently reported that the development of hyperalgesia during chronic inflammation is regulated by macrophage polarity, often referred to as proinf...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079829/ https://www.ncbi.nlm.nih.gov/pubmed/24928142 http://dx.doi.org/10.1186/1744-8069-10-36 |