Toward a systematic understanding of cancers: a survey of the pan-cancer study

Studies on molecular aberrations of cancer patients have increased unprecedentedly in scale and accessibility, allowing large-scale integrative cross-cancer analysis. Pan-cancer study is becoming a valuable paradigm for cancer genomics. Here, we review recent advances in this field and highlight the...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoqi, Zhang, Shihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080169/
https://www.ncbi.nlm.nih.gov/pubmed/25071824
http://dx.doi.org/10.3389/fgene.2014.00194
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author Liu, Zhaoqi
Zhang, Shihua
author_facet Liu, Zhaoqi
Zhang, Shihua
author_sort Liu, Zhaoqi
collection PubMed
description Studies on molecular aberrations of cancer patients have increased unprecedentedly in scale and accessibility, allowing large-scale integrative cross-cancer analysis. Pan-cancer study is becoming a valuable paradigm for cancer genomics. Here, we review recent advances in this field and highlight the potential challenges and directions especially from the computational angle.
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spelling pubmed-40801692014-07-28 Toward a systematic understanding of cancers: a survey of the pan-cancer study Liu, Zhaoqi Zhang, Shihua Front Genet Genetics Studies on molecular aberrations of cancer patients have increased unprecedentedly in scale and accessibility, allowing large-scale integrative cross-cancer analysis. Pan-cancer study is becoming a valuable paradigm for cancer genomics. Here, we review recent advances in this field and highlight the potential challenges and directions especially from the computational angle. Frontiers Media S.A. 2014-07-03 /pmc/articles/PMC4080169/ /pubmed/25071824 http://dx.doi.org/10.3389/fgene.2014.00194 Text en Copyright © 2014 Liu and Zhang. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Liu, Zhaoqi
Zhang, Shihua
Toward a systematic understanding of cancers: a survey of the pan-cancer study
title Toward a systematic understanding of cancers: a survey of the pan-cancer study
title_full Toward a systematic understanding of cancers: a survey of the pan-cancer study
title_fullStr Toward a systematic understanding of cancers: a survey of the pan-cancer study
title_full_unstemmed Toward a systematic understanding of cancers: a survey of the pan-cancer study
title_short Toward a systematic understanding of cancers: a survey of the pan-cancer study
title_sort toward a systematic understanding of cancers: a survey of the pan-cancer study
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080169/
https://www.ncbi.nlm.nih.gov/pubmed/25071824
http://dx.doi.org/10.3389/fgene.2014.00194
work_keys_str_mv AT liuzhaoqi towardasystematicunderstandingofcancersasurveyofthepancancerstudy
AT zhangshihua towardasystematicunderstandingofcancersasurveyofthepancancerstudy

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