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Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model

Despite evidence that deregulated Notch signalling is a master regulator of multiple myeloma (MM) pathogenesis, its contribution to myeloma bone disease remains to be resolved. Notch promotes survival of human MM cells and triggers human osteoclast activity in vitro. Here, we show that inhibition of...

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Detalles Bibliográficos
Autores principales:	Schwarzer, R, Nickel, N, Godau, J, Willie, B M, Duda, G N, Cirovic, B, Leutz, A, Manz, R, Bogen, B, Dörken, B, Jundt, F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080208/ https://www.ncbi.nlm.nih.gov/pubmed/24927406 http://dx.doi.org/10.1038/bcj.2014.37

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