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Laminin α2 Chain-Deficiency is Associated with microRNA Deregulation in Skeletal Muscle and Plasma

microRNAs (miRNAs) are widespread regulators of gene expression, but little is known of their potential roles in congenital muscular dystrophy type 1A (MDC1A). MDC1A is a severe form of muscular dystrophy caused by mutations in the gene encoding laminin α2 chain. To gain insight into the pathophysio...

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Detalles Bibliográficos
Autores principales: Holmberg, Johan, Alajbegovic, Azra, Gawlik, Kinga Izabela, Elowsson, Linda, Durbeej, Madeleine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080261/
https://www.ncbi.nlm.nih.gov/pubmed/25071564
http://dx.doi.org/10.3389/fnagi.2014.00155