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miR-7 and miR-153 protect neurons against MPP(+)-induced cell death via upregulation of mTOR pathway

Differential expression of microRNAs (miRs) in the brain of patients with neurodegenerative diseases suggests that they may have key regulatory roles in the development of these disorders. Two such miRs, miR-7, and miR-153 have recently been shown to target α-synuclein, a protein critically involved...

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Detalles Bibliográficos
Autores principales: Fragkouli, Apostolia, Doxakis, Epaminondas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080263/
https://www.ncbi.nlm.nih.gov/pubmed/25071443
http://dx.doi.org/10.3389/fncel.2014.00182